Turinabol

Package leaflet (information for patients)

Tradename
Turinabol

Dosage form
Tablets 10 mg.

Description
Round, flat, beveled to the edge white tablets with an imprint in the form of the brand name "V" on one side.

Composition
Active ingredient: 4-chlorodehydromethyltestosterone 10 mg.
Excipients: microcrystalline cellulose 102, calcium stearate, aerosil ® 200 (hydrophilic pyrogenic silicon dioxide).

Pharmacotherapeutic group
Anabolic / androgenic steroids.

Pharmacological properties
Anabolic steroids correct corticosteroid catabolism and reverse the deep negative nitrogen balance that occurs with corticosteroid therapy. Mechanism of action: in debilitated patients, anabolic steroids stimulate cellular protein synthesis. (If the nitrogen balance is positive, then anabolism occurs.) They also induce feelings of well-being in debilitated patients by encouraging them to eat more and gain weight. Improves calcium balance and reduces bone resorption.

Indications for use
Senile and postmenopausal osteoporosis, during the recovery period after a chronic illness, surgery, burns and fractures, for tissue repair and quick recovery. During weakness associated with weight loss for weight gain, as an adjunct to thyrotoxicosis. Recommended for severely delayed maturation, when growth hormone is not produced in the required volume. Helps with arthritis as an adjunct to other pain relief medications. In geriatric patients to increase vitality, well-being and appetite. For kidney diseases such as uremia and nephrosis, a decrease in blood urea and repair of kidney tissue. It is prescribed to counteract the catabolic effects of radiation therapy and corticosteroids. When treating children with impaired childhood development, immaturity.
It can be used during rehabilitation therapy for pathologies accompanied by impaired protein synthesis, cachexia of various origins, after infectious and radiation diseases, renal and adrenal insufficiency, and toxic goiter.

Method of administration and dosage
The film-coated tablets should be swallowed whole with plenty of water. The drug should not be taken on an empty stomach.
Turi Nabol always be taken at a dosage, which is prescribed to you by your doctor. The treatment can be different, and the doses are selected individually. The daily dose of Turanab ol for adults is 10-20 mg. N rodolzhitelnost l echenie is 2-6 weeks. Method of application: Anabolic effect: Adults: 5-10 mg orally per day.
Severe depletion: Adults: 10-20 mg orally daily for 3 weeks. Thereafter, reduce to 5-10 mg per day for maintenance.

Side effects
They are not found in all people. Turanabol tablets in therapeutic doses are unlikely to cause side effects. The following side effects have been observed during long-term treatment
- liver tumors, in the elderly, hypertrophy or prostate cancer;
- changes in the blood test, low blood clotting with a tendency to bleeding;
- hypersensitivity reactions;
- agitation, insomnia, depression, confusion;
- suppression of the secretion of hormones of sexual stimulation;
- in women - signs of virilization (for example, acne, hirsutism, male-pattern alopecia, irreversible thickening of the timbre of the voice, dysmenorrhea, hypertrophy of the clitoris), hoarseness may be the first sign of a change in tone, which can be long-term and sometimes irreversible;
- absence of the menstrual cycle and inhibition of spermatogenesis;
- an increase in the mammary glands in men; - change in libido;
- fluid retention with peripheral edema, hypercalcemia (increase in calcium ions in the blood), in men and women - the progression of atherosclerosis (a pathology of fat deposition called arteries);
- nausea, vomiting, loss of appetite;
- liver dysfunction, cholestasis (difficult release of bile), jaundice (yellowing of the skin);
- acne, hirsutism (abnormal hair growth) are minor;
- delay in the body of sodium and water ions; - an increase in the concentration of certain biochemical parameters in the blood (urea in the blood, positive nitrogen balance, hypercalcemia ), especially in patients adhering to a strict sleep regimen and patients with metastatic breast cancer;
- change (increase) in liver function indicators.
- bone pain;
- irritation of the bladder;
If any of the side effects becomes serious or if you notice any side effects not mentioned in this leaflet, please tell your doctor or pharmacist.

Contraindication
- in the presence of prostate cancer
- breast cancer in men
- heart failure
- hepatic or renal decompensation
- nephrosis
- during pregnancy and lactation
It should be used with caution in children before puberty, in patients with diabetes or coronary artery disease, in people taking ACTH, corticosteroids, or anticoagulants.

Overdose
Symptoms: hepatotoxicity and intoxication. During intoxication, sweating, nausea, and vomiting may occur. These symptoms can be eliminated by reducing the dose.
Treatment: in case of signs of poisoning, induce vomiting or gastric lavage, prescribe activated charcoal and a laxative, and consult a doctor.
Intoxication and hepatotoxicity are more likely in elderly patients and especially in young children (therapeutic overdose or accidental intoxication can be very dangerous for them).

Precautions
- Pregnancy: May cause virilization in female fetuses.
- Breastfeeding: It is not known how anabolic steroids are excreted in breast milk. In accordance with the adverse reactions that may occur in infants, it is necessary to decide whether to stop breastfeeding or stop taking the drug.
- Pediatrics: The use of anabolic steroids can have serious consequences, the benefits of which should be assessed before starting therapy. Anabolic steroids can accelerate the maturation of the pineal gland in children faster than linear growth, and the effect can last up to 6 months after the drug is stopped. In any case, therapy should be monitored by X-ray studies at intervals of 3 to 6 months, and the drug should be discontinued before bone age reaches the norm for chronological age, in order to avoid the risk of deterioration in adult growth.
- Hepatotoxicity : including jaundice with or without itching. This may be associated with acute hepatitis, accompanied by pain in the right upper quadrant. The incidence of hepatocellular carcinoma has been observed with long-term treatment with high doses of androgens.
- Geriatrics: Geriatric patients taking anabolic steroids may have an increased risk of developing prostate hypertrophy and prostate carcinoma. This may be associated with acute hepatitis, accompanied by pain in the right upper quadrant. The incidence of hepatocellular carcinoma has been observed with long-term treatment with high doses of androgens.

Interaction with other medicinal products
Anabolic steroids can enhance the effect of oral anticoagulants: the dosage can be reduced to maintain prothrombin time. In diabetics, taking anabolic steroids may increase the need for insulin and oral hypoglycemic agents. Adrenocorticoids or ACTH can increase edema when used in combination with anabolic steroids. Methandienone lowers fasting blood glucose levels in both normal people and people with diabetes.

Special instructions
Peliosis of hepatitis can occur in patients receiving anabolic steroids. These cysts can be present with minimal liver dysfunction, but they are associated with a liver defect. Symptoms are often not recognized until a life-threatening liver problem or intra-abdominal bleeding develops. Discontinuation of anabolic steroid treatment usually results in complete resolution of the lesions. Tumors in liver cells have also been reported. Many of these tumors are benign and estrogen-dependent, but fatal malignant tumors have also been reported; discontinuation of the drug may lead to regression or cessation of tumor development. Even though androgen-related or anabolic steroid-associated liver tumors, they are much more vascular than other liver tumors and may not manifest until life-threatening intra-abdominal hemorrhage develops. Changes in blood lipids associated with an increased risk of arteriosclerosis in patients taking androgens and anabolic steroids. These changes include a decrease in high density lipoprotein changes and sometimes an increase in low density lipoprotein. The changes can be very noticeable and should seriously affect the risk of changes in blood lipids associated with an increased risk of arteriosclerosis in patients taking androgens and anabolic steroids

Pregnancy and elbowing
This drug should not be used during pregnancy and lactation.
During pregnancy, the drug can cause virilization in female fetuses.
During breastfeeding, it is not known how anabolic steroids are excreted in breast milk. In accordance with the adverse reactions that may occur in infants, it is necessary to decide whether to stop breastfeeding or stop taking the drug.

Influence on the ability to drive vehicles and work with mechanisms
Does not affect

Storage conditions
Store in a dry, dark place at a temperature not exceeding 25 °C, out of the reach of children.

Shelf life
3 years. Do not use after the expiration date printed on the package.

Vacation conditions
On prescription.

Packaging
Turinabol 10 mg Tablets. There are 25 tablets in a blister. 4 blisters are packed in a cardboard box together with an enclosed leaflet.